Chemofoot: Cream for hand-foot syndrome therapy

The therapeutic cream for hand-foot syndrome is a medical device in the form of a cream, rich in ingredients that form a moisturising-lubricating and protective-regenerative barrier on the skin.


Hand-foot syndrome (palmar-plantar erythrodysaesthesia): Associated with agents such as 5-fluorouracil, doxorubicin and capecitabine.

Hand-foot skin reaction (HFSR): Associated with multikinase inhibitors (Sunitinib, Axitinib…)

Prevalence: 60-80% of patients


  • Redness and tenderness.
  • Peeling of the palms of the hands and soles of the feet.
  • Dry, numb or tingling skin.


  • Moisturises and soothes irritated skin.
  • Creates an environment conducive to natural regeneration processes.
  • Reduces symptoms of itching, burning and tightness.


SyriCalm™ CLR: antipruritic, soothing and restores the skin’s protective function.
Urea: attracts and retains water. Exfoliating effect.
Omega Plus: promotes regeneration and increases the barrier of the epidermis, improves skin elasticity.
Soybean oil : increases the skin’s barrier function.
Shea butter: moisturises and lubricates the skin.
Silk proteins: prevents skin dryness, improves the epidermal barrier, reduces water loss from the skin.


Nairobi Hospital

Female patient, 45 years old

Triple negative breast cancer

Treatment : Docetaxel+Capecitabine (Xeloda)









Before                                                            After 2 tubes