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Main chemotherapeutic agents with the capacity to produce lesions in the oral mucosa

Main chemotherapeutic agents

The main chemotherapeutic agents with the capacity to produce lesions in the oral mucosa:

Alkylating agents: Busulfan, Cyclophosphamide, Mechlorethamine, Procarbazine, Thiotepa.

Anthracyclines: Daunorubicin, Doxorubicin*, Epirubicin.

Antimetabolites: Cytosine arabinoside 5-fluorouracil*, Hydroxyurea, Methotrexate*, 6-mercaptopurine, 6-thioguanine.

Antitumor antibiotics: Actinomycin D, Amsacrine, Bleomycin, Mithramycin C, Mitomycin.

Taxanes: Docetaxel, Paclitaxel

Vinca alkaloids: Vinblastine*, Vincristine, Vinorelbine.

Others: Etoposide*, Teniposide, …

* Cytostatics that produce mucositis more frequently.